Glutaminyl Cyclase Inhibitor PQ912 Improves Cognition in Mouse Models of Alzheimer’s Disease—Studies on Relation to Effective Target Occupancy-Reference-Cited by-同舟云学术

Glutaminyl Cyclase Inhibitor PQ912 Improves Cognition in Mouse Models of Alzheimer’s Disease—Studies on Relation to Effective Target Occupancy

Published:2017-04-26 Issue:1 Volume:362 Page:119-130
ISSN:0022-3565
Container-title:Journal of Pharmacology and Experimental Therapeutics
language:en
Short-container-title:J Pharmacol Exp Ther

Author:

Hoffmann Torsten,Meyer Antje,Heiser Ulrich,Kurat Stephan,Böhme Livia,Kleinschmidt Martin,Bühring Karl-Ulrich,Hutter-Paier Birgit,Farcher Martina,Demuth Hans-Ulrich,Lues Inge,Schilling Stephan

Publisher

American Society for Pharmacology & Experimental Therapeutics (ASPET)

Subject

Pharmacology,Molecular Medicine

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4. Amyloidogenic Processing of Amyloid Precursor Protein: Evidence of a Pivotal Role of Glutaminyl Cyclase in Generation of Pyroglutamate-Modified Amyloid-β

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