Design, Synthesis, and Structural Characterization of Lysine Covalent BH3 Peptides Targeting Mcl-1-Reference-Cited by-同舟云学术

Design, Synthesis, and Structural Characterization of Lysine Covalent BH3 Peptides Targeting Mcl-1

Published:2021-04-02 Issue:8 Volume:64 Page:4903-4912
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Gambini Luca¹,Udompholkul Parima¹,Baggio Carlo¹,Muralidharan Aruljothi¹,Kenjić Nikola²,Assar Zahra³,Perry J. Jefferson P.²,Pellecchia Maurizio¹^ORCID

Affiliation:

1. Division of Biomedical Sciences, School of Medicine, University of California Riverside, 900 University Avenue, Riverside, California 92521, United States

2. Department of Biochemistry, College of Natural and Agricultural Sciences, University of California Riverside, 900 University Avenue, Riverside, California 92521, United States

3. Cayman Chemical, 1180 East Ellsworth Road, Ann Arbor, Michigan 48108, United States

Funder

National Cancer Institute

National Institute of Neurological Disorders and Stroke

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.1c00005

Reference65 articles.

1. HTS by NMR for the Identification of Potent and Selective Inhibitors of Metalloenzymes