Alicyclic Ring Size Variation of 4-Phenyl-2-naphthoic Acid Derivatives as P2Y14 Receptor Antagonists

Author:

Wen Zhiwei1ORCID,Pramanik Asmita1,Lewicki Sarah A.1,Jung Young-Hwan1,Gao Zhan-Guo1,Randle John C. R.2,Cronin Chunxia3,Chen Zhoumou4,Giancotti Luigino A.4,Whitehead Gregory S.5,Liang Bruce T.3,Breton Sylvie6,Salvemini Daniela4,Cook Donald N.5ORCID,Jacobson Kenneth A.1ORCID

Affiliation:

1. Molecular Recognition Section, Laboratory of Bioorganic Chemistry, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland 20892, United States

2. Random Walk Ventures, LLC, 108 Lincoln Street Unit 6B, Boston, Massachusetts 02111, United States

3. Pat and Jim Calhoun Cardiology Center, University of Connecticut Health Center, Farmington, Connecticut 06030, United States

4. Department of Pharmacology and Physiology and the Henry and Amelia Nasrallah Center for Neuroscience, Saint Louis University School of Medicine, 1402 South Grand Blvd., St. Louis, Missouri 63104, United States

5. Immunity, Inflammation and Disease Laboratory, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, North Carolina 27709, United States

6. Centre de Recherche du CHU de Québec, Département d’Obstétrique, de Gynécologie et Reproduction, Faculté de Médecine, Université Laval, Laval, Québec G1V 4G2, Canada

Funder

National Institute of Diabetes and Digestive and Kidney Diseases

Kantum Pharma

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

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