Discovery of a Series of 4-Amide-thiophene-2-carboxyl Derivatives as Highly Potent P2Y<sub>14</sub> Receptor Antagonists for Inflammatory Bowel Disease Treatment-Reference-Cited by-同舟云学术

Discovery of a Series of 4-Amide-thiophene-2-carboxyl Derivatives as Highly Potent P2Y₁₄ Receptor Antagonists for Inflammatory Bowel Disease Treatment

Published:2024-07-03 Issue:14 Volume:67 Page:11989-12011
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Wang Yu-hang¹²,Liu Chun-xiao¹³,Zhang Yi-han¹²,Yang Ya-lian¹³,Zhao Yan¹³,Han Lu¹³,Wang Qian-qian¹²,Xiao Wen¹²,Hu Qing-hua¹³⁴^ORCID,Ding Zhen-hua¹²^ORCID,Zhou Meng-ze¹³,Jiang Cheng¹²^ORCID

Affiliation:

1. School of Pharmacy, China Pharmaceutical University, Nanjing 211198, P. R. China

2. Jiangsu Key Laboratory of Drug Design and Optimization, China Pharmaceutical University, Nanjing 211198, P. R. China

3. State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing 211198, P. R. China

4. School of Life Science and Technology, China Pharmaceutical University, Nanjing 211198, P. R. China

Funder

Qinglan Project of Jiangsu Province of China

China Postdoctoral Science Foundation

Fundamental Research Funds for the Central Universities

National Natural Science Foundation of China

Funds of Jiangsu Key Laboratory of Marine Pharmaceutical Compound Screening

Publisher

American Chemical Society (ACS)

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.4c00699

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