3-(2-Carboxyethyl)indole-2-carboxylic Acid Derivatives: Structural Requirements and Properties of Potent Agonists of the Orphan G Protein-Coupled Receptor GPR17-Reference-Cited by-同舟云学术

3-(2-Carboxyethyl)indole-2-carboxylic Acid Derivatives: Structural Requirements and Properties of Potent Agonists of the Orphan G Protein-Coupled Receptor GPR17

Published:2018-07-26 Issue:18 Volume:61 Page:8136-8154
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Baqi Younis¹,Pillaiyar Thanigaimalai²^ORCID,Abdelrahman Aliaa²,Kaufmann Olesja²,Alshaibani Samer²,Rafehi Muhammad²^ORCID,Ghasimi Saman²,Akkari Rhalid²,Ritter Kirsten²,Simon Katharina³,Spinrath Andreas³,Kostenis Evi³^ORCID,Zhao Qiang⁴,Köse Meryem²,Namasivayam Vigneshwaran²^ORCID,Müller Christa E.²^ORCID

Affiliation:

1. Department of Chemistry, Faculty of Science, Sultan Qaboos University, P.O. Box 36, 123 Muscat, Oman

2. PharmaCenter Bonn, Pharmaceutical Institute, Pharmaceutical Sciences Bonn (PSB), Pharmaceutical Chemistry I, University of Bonn, An der Immenburg 4, 53121 Bonn, Germany

3. Institute of Pharmaceutical Biology, Section Molecular-, Cellular-, and Pharmacobiology, University of Bonn, Nußallee 6, 53115 Bonn, Germany

4. CAS Key Laboratory of Receptor Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zuchongzhi Road, Pudong, Shanghai 201203, China

Funder

Bundesministerium f?r Bildung und Forschung

UCB

Bayer

Sultan Qaboos University

Evangelisches Studienwerk Villigst

Alexander von Humboldt-Stiftung

Arab-German Young Academy of Sciences and Humanities

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine