Discovery of Irreversible p97 Inhibitors-Reference-Cited by-同舟云学术

Discovery of Irreversible p97 Inhibitors

Published:2019-03-04 Issue:5 Volume:62 Page:2814-2829
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Ding Rui¹,Zhang Ting²,Wilson Daniel J.¹,Xie Jiashu¹,Williams Jessica¹,Xu Yue²,Ye Yihong²,Chen Liqiang¹^ORCID

Affiliation:

1. Center for Drug Design, College of Pharmacy, University of Minnesota, Minneapolis, Minnesota 55455, United States

2. Laboratory of Molecular Biology, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland 20892, United States

Funder

National Institute of Diabetes and Digestive and Kidney Diseases

Center for Drug Design, University of Minnesota

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.9b00144

Reference61 articles.

1. A Zone Classification System for Risk Assessment of Idiosyncratic Drug Toxicity Using Daily Dose and Covalent Binding

2. The resurgence of covalent drugs

3. Covalent inhibitors in drug discovery: from accidental discoveries to avoided liabilities and designed therapies

4. Covalent Modifiers: A Chemical Perspective on the Reactivity of α,β-Unsaturated Carbonyls with Thiols via Hetero-Michael Addition Reactions

5. A Mighty “Protein Extractor” of the Cell: Structure and Function of the p97/CDC48 ATPase

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