Quantitative Expression Profile of Hepatobiliary Transporters in Sandwich Cultured Rat and Human Hepatocytes
Author:
Affiliation:
1. Department of Pharmacokinetics, Dynamics, and Metabolism, Pfizer Global Research & Development, St. Louis Laboratories, and Groton Laboratories, Pfizer Inc, St. Louis, Missouri
Publisher
American Chemical Society (ACS)
Subject
Drug Discovery,Pharmaceutical Science,Molecular Medicine
Link
https://pubs.acs.org/doi/pdf/10.1021/mp900044x
Reference44 articles.
1. The biology of the bile canaliculus, 1993
2. A novel method for the determination of biliary clearance in humans
3. Use of canalicular membrane vesicles (CMVs) from rats, dogs, monkeys and humans to assess drug transport across the canalicular membrane
4. Role of transport proteins in drug absorption, distribution and excretion
Cited by 71 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. CYP7A1 Gene Induction via SHP-Dependent or Independent Mechanisms can Increase the Risk of Drug-Induced Liver Injury Independently or in Synergy with BSEP Inhibition;Drug Metabolism and Disposition;2024-03-14
2. Organotypic and Microphysiological Human Tissue Models for Drug Discovery and Development—Current State-of-the-Art and Future Perspectives;Pharmacological Reviews;2022-01
3. Application of proteomic data in the translation of in vitro observations to associated clinical outcomes;Drug Discovery Today: Technologies;2021-12
4. Overcoming the shortcomings of the extended-clearance concept: a framework for developing a physiologically-based pharmacokinetic (PBPK) model to select drug candidates involving transporter-mediated clearance;Expert Opinion on Drug Metabolism & Toxicology;2021-06-15
5. Improving the Translation of Organic Anion Transporting Polypeptide Substrates using HEK293 Cell Data in the Presence and Absence of Human Plasma via PBPK Modeling;Drug Metabolism and Disposition;2021-05-06
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3