Overcoming the shortcomings of the extended-clearance concept: a framework for developing a physiologically-based pharmacokinetic (PBPK) model to select drug candidates involving transporter-mediated clearance-Reference-Cited by-同舟云学术

Overcoming the shortcomings of the extended-clearance concept: a framework for developing a physiologically-based pharmacokinetic (PBPK) model to select drug candidates involving transporter-mediated clearance

Published:2021-06-15 Issue:8 Volume:17 Page:869-886
ISSN:1742-5255
Container-title:Expert Opinion on Drug Metabolism & Toxicology
language:en
Short-container-title:Expert Opinion on Drug Metabolism & Toxicology

Author:

Liang Xiaomin¹,Lai Yurong¹^ORCID

Affiliation:

1. Drug Metabolism, Gilead Sciences Inc., Foster City, CA, USA

Funder

Gilead Sciences Inc

Publisher

Informa UK Limited

Subject

Pharmacology,Toxicology,General Medicine

Link

https://www.tandfonline.com/doi/pdf/10.1080/17425255.2021.1912012

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5. Animal scale-up

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