A 20-Year Research Overview: Quantitative Prediction of Hepatic Clearance Using the In Vitro-In Vivo Extrapolation Approach Based on Physiologically Based Pharmacokinetic Modeling and Extended Clearance Concept-Reference-Cited by-同舟云学术

A 20-Year Research Overview: Quantitative Prediction of Hepatic Clearance Using the In Vitro-In Vivo Extrapolation Approach Based on Physiologically Based Pharmacokinetic Modeling and Extended Clearance Concept

Published:2023-07-05 Issue:9 Volume:51 Page:1067-1076
ISSN:0090-9556
Container-title:Drug Metabolism and Disposition
language:en
Short-container-title:Drug Metab Dispos

Author:

Sugiyama Yuichi,Aoki Yasunori^ORCID

Publisher

American Society for Pharmacology & Experimental Therapeutics (ASPET)

Subject

Pharmaceutical Science,Pharmacology

Reference72 articles.

1. Small-molecule compounds exhibiting target-mediated drug disposition (TMDD): a minireview;An;J Clin Pharmacol,2017

2. Cluster Gauss–Newton method;Aoki;Optim Eng,2022

3. Comprehensive PBPK model of rifampicin for quantitative prediction of complex drug-drug interactions: CYP3A/2C9 induction and OATP inhibition effects;Asaumi;CPT Pharmacometrics Syst Pharmacol,2018

4. Comprehensive Evaluation of the Utility of 20 Endogenous Molecules as Biomarkers of OATP1B Inhibition Compared with Rosuvastatin and Coproporphyrin I

5. BDDCS Applied to Over 900 Drugs

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