Improving the Translation of Organic Anion Transporting Polypeptide Substrates using HEK293 Cell Data in the Presence and Absence of Human Plasma via PBPK Modeling-Reference-Cited by-同舟云学术

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Improving the Translation of Organic Anion Transporting Polypeptide Substrates using HEK293 Cell Data in the Presence and Absence of Human Plasma via PBPK Modeling

Published:2021-05-06 Issue: Volume: Page:DMD-AR-2020-000315
ISSN:0090-9556
Container-title:Drug Metabolism and Disposition
language:en
Short-container-title:Drug Metab Dispos

Author:

Bowman Christine M.,Chen Buyun,Cheong Jonathan,Liu Liling,Chen Yuan,Mao Jialin

Publisher

American Society for Pharmacology & Experimental Therapeutics (ASPET)

Subject

Pharmaceutical Science,Pharmacology

Cited by 7 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Drug transporters in drug disposition – highlights from the year 2023;Drug Metabolism Reviews;2024-09-11

2. Albumin-Mediated Drug Uptake by Organic Anion Transporter 1/3 Is Real: Implications for the Prediction of Active Renal Secretion Clearance;Molecular Pharmaceutics;2024-08-21

3. Plasma protein-mediated uptake and contradictions to the free drug hypothesis: a critical review;Drug Metabolism Reviews;2023-04-12

4. Evaluation of bottom‐up modeling of the blood–brain barrier to improve brain penetration prediction via physiologically based pharmacokinetic modeling;Biopharmaceutics & Drug Disposition;2023-02

5. Application of Empirical Scalars To Enable Early Prediction of Human Hepatic Clearance Using In Vitro-In Vivo Extrapolation in Drug Discovery: An Evaluation of 173 Drugs;Drug Metabolism and Disposition;2022-05-30

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