A novel method for the determination of biliary clearance in humans

Author:

Ghibellini Giulia,Johnson Brendan M.,Kowalsky Richard J.,Heizer William D.,Brouwer Kim L. R.

Publisher

Springer Science and Business Media LLC

Subject

Pharmaceutical Science

Reference24 articles.

1. Lipinski CA, Lombardo F, Dominy BW, Feeney PJ. Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings.Adv Drug Deliv Rev. 2001;46:3–26.

2. Fleck C, Braunlich H. Factors determining the relationship between renal and hepatic excretion of xenobiotics.Arzneimittelforschung. 1990;40:942–946.

3. US Food and Drug Administration Center for Drug Evaluation and Research.Guidance for Industry: In Vivo Drug Metabolism/Drug Interaction Studies-Study Design, Data Analysis and Recommendations for Dosing and Labeling Drug. Rockville, MD: FDA Information Branch; November 1999.

4. Liu X, Chism JP, LeCluyse EL, Brouwer KR, Brouwer KL. Correlation of biliary excretion in sandwich-cultured rat hepatocytes and in vivo in rats.Drug Metab Dispos. 1999;27:637–644.

5. Acocella G, Mattiussi R, Nicolis FB, Pallanza R, Tenconi TL. Biliary excretion of antibiotics in man.Gut. 1968;9:536–545.

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