Efficient and Facile Synthesis of Acrylamide Libraries for Protein-Guided Tethering
Author:
Affiliation:
1. Global Discovery Chemistry, Novartis Horsham Research Centre, Wimblehurst Road, Horsham RH12 5AB, U.K.
2. Department of Chemistry, Imperial College London, South Kensington Campus, London SW7 2AZ, U.K.
Publisher
American Chemical Society (ACS)
Subject
Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/ol503486t
Reference18 articles.
1. Kinetic Template-Guided Tethering of Fragments
2. Tethering: Fragment-Based Drug Discovery
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4. FP tethering: a screening technique to rapidly identify compounds that disrupt protein–protein interactions
5. “Covalent Capture”: Verschmelzung von kovalenter und nichtkovalenter Synthese
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