A Fragment-Based Method to Discover Irreversible Covalent Inhibitors of Cysteine Proteases-Reference-Cited by-同舟云学术

A Fragment-Based Method to Discover Irreversible Covalent Inhibitors of Cysteine Proteases

Published:2014-05-28 Issue:11 Volume:57 Page:4969-4974
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Kathman Stefan G.¹,Xu Ziyang¹,Statsyuk Alexander V.¹

Affiliation:

1. Department of Chemistry, Center for Molecular Innovation and Drug Discovery, Chemistry of Life Processes Institute, Northwestern University, 2170 Campus Drive, Evanston, Illinois 60208, United States

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm500345q

Reference24 articles.

1. Fragment-Based Approaches in Drug Discovery and Chemical Biology

2. Site-directed ligand discovery

3. Tethering: Fragment-Based Drug Discovery

4. Electrophilic Fragment-Based Design of Reversible Covalent Kinase Inhibitors

5. The resurgence of covalent drugs

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