Influence of Lipophilicity on the Antibacterial Activity of Polymyxin Derivatives and on Their Ability to Act as Potentiators of Rifampicin-Reference-Cited by-同舟云学术

Influence of Lipophilicity on the Antibacterial Activity of Polymyxin Derivatives and on Their Ability to Act as Potentiators of Rifampicin

Published:2021-03-10 Issue:4 Volume:7 Page:894-905
ISSN:2373-8227
Container-title:ACS Infectious Diseases
language:en
Short-container-title:ACS Infect. Dis.

Author:

Brown Pamela¹²^ORCID,Abdulle Omar¹,Boakes Steven¹,Divall Naomi¹,Duperchy Esther¹,Ganeshwaran Sonia¹,Lester Roy¹,Moss Stephen³,Rivers Dean¹,Simonovic Mona¹,Singh Jaspal¹,Stanway Steven³,Wilson Antoinette³,Dawson Michael J.¹²

Affiliation:

1. Cantab Anti-Infectives Ltd., BioPark, Broadwater Road, Welwyn Garden City AL7 3AX, United Kingdom

2. Spero Therapeutics Inc., 675 Massachusetts Avenue, 14th Floor, Cambridge, Massachusetts 02139, United States

3. Eurofins Integrated Discovery UK Ltd., Fyfield Business & Research Park, Fyfield Road, Ongar, Essex CM5 0GS, United Kingdom

Funder

National Institute of Allergy and Infectious Diseases

Innovate UK

Publisher

American Chemical Society (ACS)

Subject

Infectious Diseases

Link

https://pubs.acs.org/doi/pdf/10.1021/acsinfecdis.0c00917

Reference30 articles.

1. Colistin treatment in patients with ICU-acquired infections caused by multiresistant Gram-negative bacteria: the renaissance of an old antibiotic

2. Framework for optimisation of the clinical use of colistin and polymyxin B: the Prato polymyxin consensus

3. The “Old” and the “New” Antibiotics for MDR Gram-Negative Pathogens: For Whom, When, and How

4. β-lactam/β-lactamase inhibitor combinations: an update

5. Development of new polymyxin derivatives for multi-drug resistant Gram-negative infections

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