Influence of Lipophilicity on the Antibacterial Activity of Polymyxin Derivatives and on Their Ability to Act as Potentiators of Rifampicin

Author:

Brown Pamela12ORCID,Abdulle Omar1,Boakes Steven1,Divall Naomi1,Duperchy Esther1,Ganeshwaran Sonia1,Lester Roy1,Moss Stephen3,Rivers Dean1,Simonovic Mona1,Singh Jaspal1,Stanway Steven3,Wilson Antoinette3,Dawson Michael J.12

Affiliation:

1. Cantab Anti-Infectives Ltd., BioPark, Broadwater Road, Welwyn Garden City AL7 3AX, United Kingdom

2. Spero Therapeutics Inc., 675 Massachusetts Avenue, 14th Floor, Cambridge, Massachusetts 02139, United States

3. Eurofins Integrated Discovery UK Ltd., Fyfield Business & Research Park, Fyfield Road, Ongar, Essex CM5 0GS, United Kingdom

Funder

National Institute of Allergy and Infectious Diseases

Innovate UK

Publisher

American Chemical Society (ACS)

Subject

Infectious Diseases

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