β-lactam/β-lactamase inhibitor combinations: an update-Reference-Cited by-同舟云学术

β-lactam/β-lactamase inhibitor combinations: an update

Published:2018 Issue:9 Volume:9 Page:1439-1456
ISSN:2040-2503
Container-title:MedChemComm
language:en
Short-container-title:Med. Chem. Commun.

Author:

Tehrani Kamaleddin H. M. E.¹²³⁴⁵,Martin Nathaniel I.¹²³⁴⁵^ORCID

Affiliation:

1. Department of Chemical Biology & Drug Discovery

2. Utrecht Institute for Pharmaceutical Sciences

3. Utrecht University

4. 3584 CG Utrecht

5. The Netherlands

Abstract

Antibiotic resistance caused by β-lactamase production continues to present a growing challenge to the efficacy of β-lactams and their role as the most important class of clinically used antibiotics.

Funder

Nederlandse Organisatie voor Wetenschappelijk Onderzoek

H2020 European Research Council

Publisher

Royal Society of Chemistry (RSC)

Subject

Pharmaceutical Science,Biochemistry,Drug Discovery,Molecular Medicine,Pharmacology,Organic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2018/MD/C8MD00342D

Reference170 articles.

1. The structure of β-lactamases

2. A functional classification scheme for beta-lactamases and its correlation with molecular structure

3. Three Decades of β-Lactamase Inhibitors

4. Past and Present Perspectives on β-Lactamases

5. Metallo-β-Lactamases: Structural Features, Antibiotic Recognition, Inhibition, and Inhibitor Design

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