Integrating Intramolecular Hydrogen Bonding (IMHB) Considerations in Drug Discovery Using ΔlogP As a Tool
Author:
Affiliation:
1. Worldwide Medicinal Chemistry, Pfizer Global Research & Development, Pfizer, Inc., Groton, Connecticut 06340, United States
2. Molecular Biotechnology and Health Sciences Department, University of Torino, via Quarello 15, 10135 Torino, Italy
Publisher
American Chemical Society (ACS)
Subject
Drug Discovery,Molecular Medicine
Link
https://pubs.acs.org/doi/pdf/10.1021/jm301850m
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3. Influence of Conformation and Intramolecular Hydrogen Bonding on the Acyl Glucuronidation and Biliary Excretion of Acetylenic Bis-Dipyrrinones Related to Bilirubin
4. Predicting and Improving the Membrane Permeability of Peptidic Small Molecules
5. Intramolecular hydrogen bonding: A potential strategy for more bioavailable inhibitors of neuronal nitric oxide synthase
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