Influence of Conformation and Intramolecular Hydrogen Bonding on the Acyl Glucuronidation and Biliary Excretion of Acetylenic Bis-Dipyrrinones Related to Bilirubin-Reference-Cited by-同舟云学术

Influence of Conformation and Intramolecular Hydrogen Bonding on the Acyl Glucuronidation and Biliary Excretion of Acetylenic Bis-Dipyrrinones Related to Bilirubin

Published:2007-01-11 Issue:3 Volume:50 Page:480-488
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

McDonagh Antony F.¹,Lightner David A.¹

Affiliation:

1. Division of Gastroenterology, University of California, San Francisco, California 94143-0538, and Department of Chemistry, University of Nevada, Reno, Nevada 89557-0020

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm0609521

Reference28 articles.

1. Solvent-dependent conformation and hydrogen-bonding capacity of cyclosporin A: evidence from partition coefficients and molecular dynamics simulations

2. Identification and Characterization of Functional Hepatocyte Nuclear Factor 1‐Binding Sites in UDP‐Glucuronosyltransferase Genes

3. ABC of oral bioavailability: transporters as gatekeepers in the gut

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