Tetrahydroisoquinoline Phenols: Selective Estrogen Receptor Downregulator Antagonists with Oral Bioavailability in Rat-Reference-Cited by-同舟云学术

Tetrahydroisoquinoline Phenols: Selective Estrogen Receptor Downregulator Antagonists with Oral Bioavailability in Rat

Published:2015-12-23 Issue:1 Volume:7 Page:94-99
ISSN:1948-5875
Container-title:ACS Medicinal Chemistry Letters
language:en
Short-container-title:ACS Med. Chem. Lett.

Author:

Scott James S.¹,Bailey Andrew¹,Davies Robert D. M.¹,Degorce Sébastien L.¹,MacFaul Philip A.¹,Gingell Helen¹,Moss Thomas¹,Norman Richard A.¹,Pink Jennifer H.¹,Rabow Alfred A.¹,Roberts Bryan¹,Smith Peter D.¹

Affiliation:

1. Oncology iMed, AstraZeneca, Mereside, Alderley Park, Macclesfield, SK10 4TG, U.K.

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Drug Discovery,Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acsmedchemlett.5b00413

Reference13 articles.

1. Estrogen Receptors as Therapeutic Targets in Breast Cancer

2. Tamoxifen: a most unlikely pioneering medicine

3. Discovery and Preclinical Pharmacology of a Novel, Potent, Nonsteroidal Estrogen Receptor Agonist/Antagonist, CP-336156, a Diaryltetrahydronaphthalene

4. Fulvestrant - A Novel Endocrine Therapy for Breast Cancer

5. Investigation of (E)-3-[4-(2-Oxo-3-aryl-chromen-4-yl)oxyphenyl]acrylic Acids as Oral Selective Estrogen Receptor Down-Regulators

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