Creation of Fluorescent RXR Antagonists Based on CBTF-EE and Application to a Fluorescence Polarization Binding Assay-Reference-Cited by-同舟云学术

Creation of Fluorescent RXR Antagonists Based on CBTF-EE and Application to a Fluorescence Polarization Binding Assay

Published:2021-05-07 Issue:6 Volume:12 Page:1024-1029
ISSN:1948-5875
Container-title:ACS Medicinal Chemistry Letters
language:en
Short-container-title:ACS Med. Chem. Lett.

Author:

Takioku Maho¹,Takamura Yuta¹^ORCID,Fujihara Michiko¹²,Watanabe Masaki¹^ORCID,Yamada Shoya¹³,Kawasaki Mayu⁴,Ito Sohei⁴^ORCID,Nakano Shogo⁴^ORCID,Kakuta Hiroki¹^ORCID

Affiliation:

1. Division of Pharmaceutical Sciences, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, 1-1-1, Tsushima-Naka, Kita-ku, Okayama 700-8530, Japan

2. AIBIOS Co. Ltd., Tri-Seven Roppongi 8F 7-7-7 Roppongi, Minato-ku, Tokyo 106-0032, Japan

3. Research Fellowship Division, Japan Society for the Promotion of Science, Sumitomo-Ichibancho FS Bldg., 8 Ichibancho, Chiyoda-ku, Tokyo 102-8472, Japan

4. Graduate School of Integrated Pharmaceutical and Nutritional Sciences, University of Shizuoka, 52- 1 Yada, Suruga-ku, Shizuoka 422-8526, Japan

Funder

Japan Society for the Promotion of Science

Okayama Foundation for Science and Technology

Kobayashi Foundation

The Tokyo Biochemical Research Foundation

Shoshisha Foundation

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Drug Discovery,Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acsmedchemlett.1c00201

Reference33 articles.

1. World Health Organization. World health Statistics 2020: Monitoring Health for the SDGs, Sustainable Development Goals. 2020. https://apps.who.int/iris/handle/10665/332070.

2. Beyond Obesity and Lifestyle: A Review of 21st Century Chronic Disease Determinants

3. Retinoid X receptor ligands: a patent review (2007 – 2013)

4. Nuclear Receptors, RXR, and the Big Bang

5. International Union of Pharmacology. LXIII. Retinoid X Receptors

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