Process Research on the Asymmetric Hydrogenation of a Benzophenone for Developing the Manufacturing Process of the Squalene Synthase Inhibitor TAK-475-Reference-Cited by-同舟云学术

Process Research on the Asymmetric Hydrogenation of a Benzophenone for Developing the Manufacturing Process of the Squalene Synthase Inhibitor TAK-475

Published:2011-08-26 Issue:5 Volume:15 Page:1178-1184
ISSN:1083-6160
Container-title:Organic Process Research & Development
language:en
Short-container-title:Org. Process Res. Dev.

Author:

Goto Mitsutaka¹,Konishi Takahiro,Kawaguchi Shinji,Yamada Masatoshi,Nagata Toshiaki,Yamano Mitsuhisa

Affiliation:

1. Chemical Technology Department, Takeda Pharmaceutical Co. Ltd., 4720, Takeda, Mitsui, Hikari, Yamaguchi 743-8502, Japan

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Physical and Theoretical Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/op2001673

Reference62 articles.

1. Synthesis of Novel 4,1-Benzoxazepine Derivatives as Squalene Synthase Inhibitors and Their Inhibition of Cholesterol Synthesis

2. Syntheses of fused heterocyclic compounds and their inhibitory activities for squalene synthase

3. Syntheses of medium-sized heterocycles using an intramolecular Michael reaction.

4. WO/2005/121133 A1 2005.

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