The Cardiovascular Effects of a Meal: J‐T peak and T peak ‐T end Assessment and Further Insights Into the Physiological Effects-Reference-Cited by-同舟云学术

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The Cardiovascular Effects of a Meal: J‐T peak and T peak ‐T end Assessment and Further Insights Into the Physiological Effects

Published:2019-01-11 Issue:6 Volume:59 Page:799-810
ISSN:0091-2700
Container-title:The Journal of Clinical Pharmacology
language:en
Short-container-title:The Journal of Clinical Pharmacology

Author:

Täubel Jörg¹²,Ferber Georg³,Langenhoven Leen¹,del Bianco Teresa¹,Fernandes Sara¹,Djumanov Dilshat¹,Kanters Jørgen K.⁴,Graff Claus⁵,Camm A. John²

Affiliation:

1. Richmond Pharmacology Ltd.St George's University of London Cranmer Terrace London UK

2. Cardiovascular and Cell Sciences Research InstituteSt George's University of London London UK

3. Statistik Georg Ferber GmbHCagliostrostrasse Riehen Switzerland

4. Department of Biomedical SciencesFaculty of Health and Medical SciencesUniversity of Copenhagen Copenhagen Denmark

5. Department of Health Science and TechnologyAalborg University Aalborg Denmark

Publisher

Wiley

Subject

Pharmacology (medical),Pharmacology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/jcph.1374

Reference39 articles.

1. Shortening of the QT Interval After Food Can Be Used to Demonstrate Assay Sensitivity in Thorough QT Studies

2. Single Doses up to 800 mg of E-52862 Do Not Prolong the QTc Interval – A Retrospective Validation by Pharmacokinetic-Pharmacodynamic Modelling of Electrocardiography Data Utilising the Effects of a Meal on QTc to Demonstrate ECG Assay Sensitivity

3. Influence of Meals and Glycemic Changes on QT Interval Dynamics

4. Stability of the Effect of a Standardized Meal on QTc

5. Use of Early Clinical Trial Data to Support Thorough QT Study Waiver for Upadacitinib and Utility of Food Effect to Demonstrate ECG Assay Sensitivity

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1. Short-term high-calorie high-fat feeding induces hyperinsulinemia and blunts skeletal muscle microvascular blood flow in healthy humans;American Journal of Physiology-Endocrinology and Metabolism;2024-07-01

2. Pooled analysis of routine safety parameters observed in healthy participants at baseline and following placebo administration in early phase clinical studies;Clinical and Translational Science;2024-01

3. Data-Driven Classifiers for Early Meal Detection Using ECG;IEEE Sensors Letters;2023-09

4. Effect of hyperglycaemia in combination with moxifloxacin on cardiac repolarization in male and female patients with type I diabetes;Clinical Research in Cardiology;2022-05-21

5. How to Successfully Generate an Alternative Approach to a Thorough QT Study: GLPG1972 as an Example;Clinical Pharmacology & Therapeutics;2022-04-27

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