Single Doses up to 800 mg of E-52862 Do Not Prolong the QTc Interval – A Retrospective Validation by Pharmacokinetic-Pharmacodynamic Modelling of Electrocardiography Data Utilising the Effects of a Meal on QTc to Demonstrate ECG Assay Sensitivity-Reference-Cited by-同舟云学术

Single Doses up to 800 mg of E-52862 Do Not Prolong the QTc Interval – A Retrospective Validation by Pharmacokinetic-Pharmacodynamic Modelling of Electrocardiography Data Utilising the Effects of a Meal on QTc to Demonstrate ECG Assay Sensitivity

Published:2015-08-20 Issue:8 Volume:10 Page:e0136369
ISSN:1932-6203
Container-title:PLOS ONE
language:en
Short-container-title:PLoS ONE

Author:

Täubel Jörg,Ferber Georg,Lorch Ulrike,Wang Duolao,Sust Mariano,Camm A. John

Publisher

Public Library of Science (PLoS)

Subject

Multidisciplinary

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5. The IQ-CSRC prospective clinical Phase 1 study: "Can early QT assessment using exposure response analysis replace the thorough QT study?";B Darpo;Ann Noninvasive Electrocardiol,2014

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