Stability of the Effect of a Standardized Meal on QTc
Author:
Affiliation:
1. Richmond Pharmacology Ltd.; St George's University of London; London United Kingdom
2. Statistik Georg Ferber GmbH; Riehen Switzerland
Publisher
Wiley
Subject
Physiology (medical),Cardiology and Cardiovascular Medicine,General Medicine
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1111/anec.12371/fullpdf
Reference17 articles.
1. The IQ-CSRC prospective clinical phase I study: Can early QT assessment using exposure response analysis replace the thorough QT study?;Darpo;Ann Noninvasive Electrocardiol,2014
2. Results from the IQ-CSRC prospective study support replacement of the thorough QT study by QT assessment in the early clinical phase;Darpo;Clin Pharmacol Ther,2015
3. Shortening of the QT interval after food can be used to demonstrate assay sensitivity in thorough QT studies;Taubel;J Clin Pharmacol,2012
4. QTc changes after meal intake: Sex differences and correlates;Hnatkova;J Electrocardiol,2014
5. Reproducibility of QTc interval changes after meal intake;Hnatkova;J Electrocardiol,2015
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