Design and synthesis of leucine‐linked quinazoline‐4(3 H )‐one‐sulphonamide molecules distorting malarial reductase activity in the folate pathway-Reference-Cited by-同舟云学术

Design and synthesis of leucine‐linked quinazoline‐4(3 H )‐one‐sulphonamide molecules distorting malarial reductase activity in the folate pathway

Published:2019-08-05 Issue:9 Volume:352 Page:1900099
ISSN:0365-6233
Container-title:Archiv der Pharmazie
language:en
Short-container-title:Arch Pharm Chem Life Sci

Author:

Patel Tarosh S.¹,Bhatt Jaimin D.²,Dixit Ritu B.³,Chudasama Chaitanya J.⁴,Patel Bhavesh D.⁵,Dixit Bharat C.¹^ORCID

Affiliation:

1. Chemistry Department, V. P. & R. P. T. P Science CollegeAffiliated to Sardar Patel University Vallabh Vidyanagar Gujarat India

2. Industrial Chemistry Department, V. P. & R. P. T. P Science CollegeAffiliated to Sardar Patel University Vallabh Vidyanagar Gujarat India

3. Pharmaceutical Chemistry DepartmentAshok & Rita Patel Institute of Integrated Studies and Research in Biotechnology and Allied Sciences New Vallabh Vidyanagar Gujarat India

4. Department of Biochemistry, Shree Alpesh N. Patel P. G. InstituteAffiliated to Sardar Patel University Anand Gujarat India

5. Microbiology Department, V. P. & R. P. T. P Science CollegeAffiliated to Sardar Patel University Vallabh Vidyanagar Gujarat India

Funder

University Grants Commission

Publisher

Wiley

Subject

Drug Discovery,Pharmaceutical Science

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/ardp.201900099

Reference60 articles.

1. WHO World Malaria Report 2018 World Health Organization 2018:https://www.who.int/malaria/publications/world‐malaria‐report‐2018/report/en/.

2. Towards an understanding of drug resistance in malaria: Three-dimensional structure of Plasmodium falciparum dihydrofolate reductase by homology building

3. Drug Resistance in Malaria Parasites of Animals and Man

4. The mode of action and the mechanism of resistance to antimalarial drugs

5. Malaria: New Developments in Treatment and Prevention

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