Sulfonamide based pyrimidine derivatives combating <i>Plasmodium</i> parasite by inhibiting falcipains-2 and falcipains-3 as antimalarial agents-Reference-Cited by-同舟云学术

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Sulfonamide based pyrimidine derivatives combating Plasmodium parasite by inhibiting falcipains-2 and falcipains-3 as antimalarial agents

Published:2024 Issue:34 Volume:14 Page:24725-24740
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Rahman Abdur¹,Anjum Shazia¹,Bhatt Jaimin D.²,Dixit Bharat C.²,Singh Anju¹,khan Sabiha¹,Fatima Sadaf¹,Patel Tarosh S.²^ORCID,Hoda Nasimul¹^ORCID

Affiliation:

1. Drug Design and Synthesis Lab., Department of Chemistry, Jamia Millia Islamia, Jamia Nagar, New Delhi 110025, India

2. Chemistry Department, V. P. & R. P. T. P Science College, Affiliated to Sardar Patel University, Vallabh Vidyanagar 388120, Gujarat, India

Abstract

In this report, we present the design and synthesis of a novel series of pyrimidine-tethered spirochromane-based sulfonamide derivatives aimed at combating drug resistance in malaria.

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/RA/D4RA04370G

Reference68 articles.

1. Malaria

2. Malaria: Biology and Disease

3. Malaria: progress, perils, and prospects for eradication

4. World Health Organization , World Malaria Report 2023 , Geneva , 2023

5. Spread of Artemisinin Resistance in Plasmodium falciparum Malaria

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