Side‐by‐side comparability of batch and continuous downstream for the production of monoclonal antibodies-Reference-Cited by-同舟云学术

Side‐by‐side comparability of batch and continuous downstream for the production of monoclonal antibodies

Published:2020-01-29 Issue:4 Volume:117 Page:1024-1036
ISSN:0006-3592
Container-title:Biotechnology and Bioengineering
language:en
Short-container-title:Biotechnology and Bioengineering

Author:

David Laura¹^ORCID,Schwan Peter²,Lobedann Martin²,Borchert Sven‐Oliver²,Budde Bastian²,Temming Maike²,Kuerschner Mike²,Alberti Aguilo Francisca Maria²,Baumarth Kerstin²,Thüte Tobias²,Maiser Benjamin²,Blank Andreas²,Kistler Viktorija²,Weber Nils²,Brandt Heiko²,Poggel Martin²,Kaiser Klaus²,Geisen Karl²,Oehme Felix²,Schembecker Gerhard³

Affiliation:

1. Invite GmbH Leverkusen Germany

2. Bayer AG Leverkusen Germany

3. BCI, Plant and Process Design TU Dortmund University Dortmund Germany

Funder

European Regional Development Fund

Bundesministerium für Bildung und Forschung

Publisher

Wiley

Subject

Applied Microbiology and Biotechnology,Bioengineering,Biotechnology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/bit.27267

Reference18 articles.

1. Bernshausen J Lobedann M &Schwan P.2016.Process control system for regulating and controlling a modular system for the production of biopharmaceutical and biological macromolecular products. BR112017024373 (A2).

2. BioPhorum.2019.Biomanufacturing technology roadmap.Continuous downstream processing for biomanufacturing.https://www.biophorum.com/continuous‐downstream‐processing‐for‐biomanufacturing‐an‐industry‐review/(accessed 06.11.2019).

3. Single‐use, continuous‐countercurrent, multicolumn chromatography;Bisschops M.;BioProcess International,2009

4. Online integrity monitoring in the Protein A step of mAb Production Processes-increasing reliability and process robustness

5. Information Technologies for Innovative Process and Plant Design

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