Oxidative activation of proguanil and dapsone acetylation in Thai soldiers.
Author:
Publisher
Wiley
Subject
Pharmacology (medical),Pharmacology
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1111/j.1365-2125.1994.tb04241.x/fullpdf
Reference18 articles.
1. The pharmacokinetics and activation of proguanil in man: consequences of variability in drug metabolism;Helsby;Br J clin Pharmac,1990
2. Inter-subject variability in the metabolism of proguanil to the active metabolite cycloguanil in man;Ward;Br J clin Pharmac,1989
3. Variability in the metabolism of proguanil to the active metabolite cycloguanil in healthy Kenyan adults;Watkins;Trans Roy Soc Trop Med Hyg,1990
4. In vitro metabolism of the biguanide antimalarials in human liver microsomes: evidence for a role of the mephenytoin hydroxylase (P450 MP) enzyme;Helsby;Br J clin Pharmac,1990
5. Mephenytoin hydroxylation deficiency in Caucasians: Frequency of a new oxidative drug metabolism polymorphism;Wedlund;Clin Pharmac Ther,1984
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