The pharmacokinetics and activation of proguanil in man: consequences of variability in drug metabolism.
Author:
Publisher
Wiley
Subject
Pharmacology (medical),Pharmacology
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1111/j.1365-2125.1990.tb03818.x/fullpdf
Reference13 articles.
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2. Characterization and inhibition of mephenytoin 4-hydroxylase activity in human liver microsomes;Hall;J. Pharmac. exp. Ther.,1987
3. In vitro metabolism of the biguanide antimalarials in human liver microsomes: Evidence for a role of the mephenytoin hydroxylase (P450MP) enzyme;Helsby;Br. J. clin. Pharmac,1990
4. Pharmacogenetics of mephenytoin: a new drug hydroxylation polymorphism in man;Küpfer;Eur. J. clin. Pharmac.,1984
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