γ-Secretase modulators do not induce Aβ-rebound and accumulation of β-C-terminal fragment-Reference-Cited by-同舟云学术

γ-Secretase modulators do not induce Aβ-rebound and accumulation of β-C-terminal fragment

Published:2012-03-13 Issue:2 Volume:121 Page:277-286
ISSN:0022-3042
Container-title:Journal of Neurochemistry
language:en
Short-container-title:

Author:

Li Ting,Huang Yunhong,Jin Shiyi,Ye Liang,Rong Na,Yang Xiujuan,Ding Yu,Cheng Ziqiang,Zhang Jinqiang,Wan Zehong,Harrison David C.,Hussain Ishrut,Hall Adrian,Lee Daniel Hong Seng,Lau Lit-Fui,Matsuoka Yasuji

Publisher

Wiley

Subject

Cellular and Molecular Neuroscience,Biochemistry

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1111/j.1471-4159.2011.07560.x/fullpdf

Reference43 articles.

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2. The amyloid-beta rise and gamma-secretase inhibitor potency depend on the level of substrate expression;Burton;J. Biol. Chem.,2008

3. Acute gamma-secretase inhibition of nonhuman primate CNS shifts amyloid precursor protein (APP) metabolism from amyloid-beta production to alternative APP fragments without amyloid-beta rebound;Cook;J. Neurosci.,2010

4. Independent generation of Abeta42 and Abeta38 peptide species by gamma-secretase;Czirr;J. Biol. Chem.,2008

5. Functional gamma-secretase inhibitors reduce beta-amyloid peptide levels in brain;Dovey;J. Neurochem.,2001

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