Stereospecific reduction of a potent kinesin spindle protein (KSP) inhibitor in human tissues-Reference-Cited by-同舟云学术

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Stereospecific reduction of a potent kinesin spindle protein (KSP) inhibitor in human tissues

Published:2010-05 Issue:10 Volume:79 Page:1526-1533
ISSN:0006-2952
Container-title:Biochemical Pharmacology
language:en
Short-container-title:Biochemical Pharmacology

Author:

Li Chunze,Lu Bing,Garbaccio Robert M.,Tasber Edward S.,Fraley Mark E.,Hartman George D.,Ye Jingjing,Harrelson Jane C.,Prueksaritanont Thomayant

Publisher

Elsevier BV

Subject

Pharmacology,Biochemistry

Reference27 articles.

1. Kinesin spindle protein (KSP) inhibitors. Part 1: the discovery of 3,5-diaryl-4,5-dihydropyrazoles as potent and selective inhibitors of the mitotic kinesin KSP;Cox;Bioorg Med Chem Lett,2005

2. Kinesin spindle protein (KSP) inhibitors. Part 7: design and synthesis of 3,3-disubstituted dihydropyrazolobenzoxazines as potent inhibitors of the mitotic kinesin KSP;Garbaccio;Bioorg Med Chem Lett,2007

3. Human carbonyl reduction pathways and a strategy for their study in vitro;Rosemond;Drug Metab Rev,2004

4. Multiplicity of mammalian reductases for xenobiotic carbonyl compounds;Matsunaga;Drug Metab Pharmacokinet,2006

5. Carbonyl reductases: the complex relationships of mammalian carbonyl- and quinine-reducing enzymes and their role in physiology;Oppermann;Ann Rev Pharmacol Toxicol,2007

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2. KSP Inhibitors as Antimitotic Agents;Current Topics in Medicinal Chemistry;2014-12-12

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4. Characterization of Human Liver Enzymes Involved in the Biotransformation of Boceprevir, a Hepatitis C Virus Protease Inhibitor;Drug Metabolism and Disposition;2010-12-01

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