Kinesin spindle protein (KSP) inhibitors. Part 1: The discovery of 3,5-diaryl-4,5-dihydropyrazoles as potent and selective inhibitors of the mitotic kinesin KSP-Reference-Cited by-同舟云学术

Kinesin spindle protein (KSP) inhibitors. Part 1: The discovery of 3,5-diaryl-4,5-dihydropyrazoles as potent and selective inhibitors of the mitotic kinesin KSP

Published:2005-04 Issue:8 Volume:15 Page:2041-2045
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Cox Christopher D.,Breslin Michael J.,Mariano Brenda J.,Coleman Paul J.,Buser Carolyn A.,Walsh Eileen S.,Hamilton Kelly,Huber Hans E.,Kohl Nancy E.,Torrent Maricel,Yan Youwei,Kuo Laurence C.,Hartman George D.

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference15 articles.

1. Microtubule motors in mitosis

2. Kinesin motors and disease

3. Processive and Nonprocessive Models of Kinesin Movement

4. Small Molecule Inhibitor of Mitotic Spindle Bipolarity Identified in a Phenotype-Based Screen

5. Probing Spindle Assembly Mechanisms with Monastrol, a Small Molecule Inhibitor of the Mitotic Kinesin, Eg5

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