Characterization of Human Liver Enzymes Involved in the Biotransformation of Boceprevir, a Hepatitis C Virus Protease Inhibitor-Reference-Cited by-同舟云学术

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Characterization of Human Liver Enzymes Involved in the Biotransformation of Boceprevir, a Hepatitis C Virus Protease Inhibitor

Published:2010-12-01 Issue:3 Volume:39 Page:510-521
ISSN:0090-9556
Container-title:Drug Metabolism and Disposition
language:en
Short-container-title:Drug Metab Dispos

Author:

Ghosal Anima,Yuan Yuan,Tong Wei,Su Ai-Duen,Gu Chunyan,Chowdhury Swapan K.,Kishnani Narendra S.,Alton Kevin B.

Publisher

American Society for Pharmacology & Experimental Therapeutics (ASPET)

Subject

Pharmaceutical Science,Pharmacology

Reference20 articles.

1. The Aldo-Keto Reductase Superfamily and its Role in Drug Metabolism and Detoxification

2. Development of Nonsteroidal Anti-Inflammatory Drug Analogs and Steroid Carboxylates Selective for Human Aldo-Keto Reductase Isoforms: Potential Antineoplastic Agents That Work Independently of Cyclooxygenase Isozymes

3. Boceprevir, an NS3 Protease Inhibitor of HCV

4. Carbonyl reduction of naltrexone and dolasetron by oxidoreductases isolated from human liver cytosol

5. Discovery of Small-Molecule Inhibitors of HCV NS3-4A Protease as Potential Therapeutic Agents against HCV Infection

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2. Invention of MK-7845, a SARS-CoV-2 3CL Protease Inhibitor Employing a Novel Difluorinated Glutamine Mimic;Journal of Medicinal Chemistry;2024-02-16

3. The Aldo-Keto Reductase Superfamily;Reference Module in Biomedical Sciences;2024

4. Aryl N-[ω-(6-Fluoroindol-1-yl)alkyl]carbamates as Inhibitors of Fatty Acid Amide Hydrolase, Monoacylglycerol Lipase, and Butyrylcholinesterase: Structure–Activity Relationships and Hydrolytic Stability;ACS Omega;2021-05-14

5. Evaluation of the clearance mechanism of non-CYP-mediated drug metabolism and DDI as a victim drug;Identification and Quantification of Drugs, Metabolites, Drug Metabolizing Enzymes, and Transporters;2020

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