The Potential of 19F NMR Application in GPCR Biased Drug Discovery
Author:
Funder
University of South Florida
Cell Biology, Microbiology and Molecular Biology
Publisher
Elsevier BV
Subject
Pharmacology,Toxicology
Reference87 articles.
1. Biased signalling: from simple switches to allosteric microprocessors;Smith;Nat. Rev. Drug Discov.,2018
2. Contribution of ligand structure to activation of alpha 2-adrenergic receptor subtype coupling to Gs;Eason;Mol. Pharmacol.,1994
3. Independent-arrestin 2 and G protein-mediated pathways for angiotensin II activation of extracellular signal-regulated kinases 1 and 2;Wei;Proc. Natl. Acad. Sci. U. S. A.,2003
4. Dynamic bias and its implications for GPCR drug discovery;Michel;Nat. Rev. Drug Discov.,2014
5. Quantifying ligand bias at seven-transmembrane receptors;Rajagopal;Mol. Pharmacol.,2011
Cited by 18 articles. 订阅此论文施引文献 订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献
1. G protein-coupled receptors (GPCRs): advances in structures, mechanisms and drug discovery;Signal Transduction and Targeted Therapy;2024-04-10
2. Structure and function of an intermediate GPCR-Gαβγ complex;2024-04-03
3. In‐Cell 19F NMR of Proteins: Recent Progress and Future Opportunities;Chemistry – A European Journal;2024-02-15
4. G protein-coupled receptor-biased signaling: potential drug discovery to facilitate treatment of metabolic diseases;Acta Materia Medica;2024
5. Visualizing Proteins in Human Cells at Near‐Physiological Concentrations with Sensitive 19F NMR Chemical Tags;Angewandte Chemie;2023-04-20
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线，采集、加工和组织学术论文而形成的新型学术文献查询和分析系统，可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容，当前同舟云学术共收录了国内外主流学术期刊6万余种，收集的期刊论文及会议论文总量共计约1.5亿篇，并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询！咨询电话：010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3