Biased signalling: from simple switches to allosteric microprocessors
Author:
Publisher
Springer Science and Business Media LLC
Subject
Drug Discovery,Pharmacology,General Medicine
Link
http://www.nature.com/articles/nrd.2017.229.pdf
Reference223 articles.
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3. Santos, R. et al. A comprehensive map of molecular drug targets. Nat. Rev. Drug Discov. 16, 19–34 (2017).
4. Smith, J. S. & Rajagopal, S. The β-arrestins: multifunctional regulators of G protein-coupled receptors. J. Biol Chem. 291, 8969–8977 (2016).
5. Benovic, J. L., Strasser, R. H., Caron, M. G. & Lefkowitz, R. J. β-Adrenergic receptor kinase: identification of a novel protein kinase that phosphorylates the agonist-occupied form of the receptor. Proc. Natl Acad. Sci. USA 83, 2797–2801 (1986).
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