Synthesis and pharmacological evaluation of benzannulated derivatives as potent and selective sigma-1 protein ligands

Author:

Donnier-Maréchal Marion,Carato Pascal,Le Broc Delphine,Furman Christophe,Melnyk Patricia

Funder

Lille 2 University, FRI “J'innove” PRES Univ Lille Nord de France

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Pharmacology,General Medicine

Reference41 articles.

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2. Rat liver and kidney contain high densities of sigma-1 and sigma-2 receptors: characterization by ligand binding and photoaffinity labeling;Hellewell;Eur. J. Pharmacol., Mol. Pharmacol. Sect.,1994

3. Immunocytochemical localization of the sigma1 receptor in the adult rat central nervous system;Alonso;Neuroscience,2000

4. Sigma receptors: biology and therapeutic potential;Guitart;Psychopharmacology,2004

5. A proposal for the classification of sigma binding sites;Quirion;Trends Pharmacol. Sci.,1992

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