The Chemotype of Chromanones as a Privileged Scaffold for Multineurotarget Anti-Alzheimer Agents

Author:

Keuler Tim1,Lemke Carina1,Elsinghorst Paul W.12ORCID,Iriepa Isabel3,Chioua Mourad4,Martínez-Grau María Angeles5,Beadle Christopher D.6,Vetman Tatiana7,López-Muñoz Francisco8,Wille Timo9,Bartz Ulrike10,Deuther-Conrad Winnie11,Marco-Contelles José4,Gütschow Michael1ORCID

Affiliation:

1. Pharmaceutical Institute, Pharmaceutical & Medicinal Chemistry, University of Bonn, An der Immenburg 4, 53121 Bonn, Germany

2. Central Institute of the Bundeswehr Medical Service Munich, Ingolstädter Landstraße 102, 85748 Garching Germany

3. Universidad de Alcalá, Departamento de Química Orgánica y Química Inorgánica, Ctra. Madrid-Barcelona, 28871 Alcalá de Henares, Madrid España

4. Laboratory of Medicinal Chemistry, IQOG, CSIC, C/Juan de la Cierva 3, 28006 Madrid, Spain

5. Lilly Research Laboratories, Eli Lilly & Company, Avda. de la Industria 30, 28108 Alcobendas, Madrid Spain

6. Lilly Research Centre, Eli Lilly & Company, Erl Wood Manor, Windlesham, Surrey GU20 6PH, United Kingdom

7. Lilly Research Laboratories, Eli Lilly & Company, Indianapolis, Indiana 46285, United States

8. Faculty of Health, Camilo José Cela University of Madrid (UCJC), Neuropsychopharmacology Unit, “Hospital 12 de Octubre” Research Institute, 28692 Madrid, Spain

9. Bundeswehr Institute of Pharmacology and Toxicology, Neuherbergstraße 11, 80937 München, Germany

10. Department of Natural Sciences, University of Applied Sciences Bonn-Rhein-Sieg, von-Liebig-Straße 20, 53359 Rheinbach, Germany

11. Helmholtz-Zentrum Dresden-Rossendorf, Institute of Radiopharmaceutical Cancer Research, Department of Neuroradiopharmaceuticals, 04318 Leipzig, Germany

Funder

J?rgen Manchot Stiftung

Publisher

American Chemical Society (ACS)

Subject

Pharmacology (medical),Pharmacology

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