Design and synthesis of improved active-site SHP2 inhibitors with anti-breast cancer cell effects
Author:
Funder
National Cancer Institute
West Virginia University
National Institutes of Health
Publisher
Elsevier BV
Subject
Organic Chemistry,Drug Discovery,Pharmacology,General Medicine
Reference45 articles.
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4. SHP2 is up-regulated in breast cancer cells and in infiltrating ductal carcinoma of the breast, implying its involvement in breast oncogenesis;Zhou;Histopathology,2008
5. Inhibition of SHP2 leads to mesenchymal to epithelial transition in breast cancer cells;Zhou;Cell Death Differ.,2008
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