Discovery of novel substituted pyridine carboxamide derivatives as potent allosteric SHP2 inhibitors-Reference-Cited by-同舟云学术

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Discovery of novel substituted pyridine carboxamide derivatives as potent allosteric SHP2 inhibitors

Published:2024-09 Issue: Volume: Page:116830
ISSN:0223-5234
Container-title:European Journal of Medicinal Chemistry
language:en
Short-container-title:European Journal of Medicinal Chemistry

Author:

Lv Xiashi^ORCID,Li Peifeng,Chen Zhuo,Huang Siting,Zhang Shuang,Ji Bei,Liu Jingjing,Du Tonghong,Zhang Tingting,Chen Xijing,Qiang Lei,He Yuan,Lai Yisheng

Funder

Six Talent Peaks Project in Jiangsu Province

National Natural Science Foundation of China

Publisher

Elsevier BV

Reference59 articles.

1. Crystal structure of the tyrosine phosphatase SHP-2;Hof;Cell,1998

2. The tyrosine phosphatase SHP2 in development and cancer;Grossmann;Adv. Cancer Res.,2010

3. Mechanism of activating mutations and allosteric drug inhibition of the phosphatase SHP2;Pádua;Nat. Commun.,2018

4. A comprehensive review of SHP2 and its role in cancer;Asmamaw;Cell. Oncol,2022

5. SHP2: a pleiotropic target at the interface of cancer and its microenvironment;Sodir;Cancer Discov,2023

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