Strategies Targeting Protein Tyrosine Phosphatase SHP2 for Cancer Therapy-Reference-Cited by-同舟云学术

Strategies Targeting Protein Tyrosine Phosphatase SHP2 for Cancer Therapy

Published:2022-02-14 Issue:4 Volume:65 Page:3066-3079
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Song Yihui¹²,Wang Shu¹,Zhao Min¹,Yang Xinyu¹,Yu Bin¹²^ORCID

Affiliation:

1. School of Pharmaceutical Sciences & Key Laboratory of Advanced Drug Preparation Technologies, Ministry of Education, Zhengzhou University, Zhengzhou 450001, China

2. State Key Laboratory of Natural and Biomimetic Drugs, Peking University, Beijing 100000, China

Funder

National Natural Science Foundation of China

Program for Science & Technology Innovation Talents in Universities of Henan Province

State Key Laboratory of Natural and Biomimetic Drugs

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.1c02008

Reference77 articles.

1. Crystal Structure of the Tyrosine Phosphatase SHP-2

2. An Shp2/SFK/Ras/Erk Signaling Pathway Controls Trophoblast Stem Cell Survival

3. Molecular Mechanism for a Role of SHP2 in Epidermal Growth Factor Receptor Signaling

4. The tyrosine phosphatase SHP-2 is required for mediating phosphatidylinositol 3-kinase/Akt activation by growth factors

5. SHP-2 Regulates SOCS-1-mediated Janus Kinase-2 Ubiquitination/Degradation Downstream of the Prolactin Receptor

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