5-Deazaflavin derivatives as inhibitors of p53 ubiquitination by HDM2-Reference-Cited by-同舟云学术

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5-Deazaflavin derivatives as inhibitors of p53 ubiquitination by HDM2

Published:2013-11 Issue:22 Volume:21 Page:6868-6877
ISSN:0968-0896
Container-title:Bioorganic & Medicinal Chemistry
language:en
Short-container-title:Bioorganic & Medicinal Chemistry

Author:

Dickens Michael P.,Roxburgh Patricia,Hock Andreas,Mezna Mokdad,Kellam Barrie,Vousden Karen H.,Fischer Peter M.

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference48 articles.

1. p53 in health and disease

2. Mdm2 Is a RING Finger-dependent Ubiquitin Protein Ligase for Itself and p53

3. Regulation of p53 stability by Mdm2

4. Small-molecule inhibitors of MDM2 as new anticancer therapeutics

5. Small molecule inhibitors of HDM2 ubiquitin ligase activity stabilize and activate p53 in cells

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1. Synthetic methodology of pyrimido[4,5‐b]quinoline derivatives;Journal of Heterocyclic Chemistry;2024-04-03

2. MDM2 Inhibitors for Cancer Therapy: The Past, Present, and Future;Pharmacological Reviews;2024-03-15

3. Review: synthesis and anticancer activity of pyrimido[4,5-b]quinolines in the last twenty years;Chemical Papers;2024-02-12

4. Design, synthesis, and antitumor efficacy of novel 5-deazaflavin derivatives backed by kinase screening, docking, and ADME studies;Journal of Enzyme Inhibition and Medicinal Chemistry;2023-06-21

5. Role of p53 in breast cancer progression: An insight into p53 targeted therapy;Theranostics;2023

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