Regulation of p53 stability by Mdm2
Author:
Publisher
Springer Science and Business Media LLC
Subject
Multidisciplinary
Link
http://www.nature.com/articles/387299a0.pdf
Reference30 articles.
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3. Momand, J., Zambetti, G. P., George, D. L. & Levine, A. J. The mdm-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivation. Cell 69, 1237–1245 (1992).
4. Chen, J. D., Marechal, V. & Levine, A. J. Mapping of the p53 and mdm-2 interaction domains. Mol. Cell. Biol. 13, 4107–4114 (1993).
5. Haupt, Y., Barak, Y. & Oren, M. Cell type-specific inhibition of p53-mediated apoptosis by mdm2. EMBO J. 15, 1596–1606 (1996).
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