Small-molecule inhibitors of MDM2 as new anticancer therapeutics
Author:
Publisher
Elsevier BV
Subject
Cancer Research
Reference100 articles.
1. Molecular analysis and chromosomal mapping of amplified genes isolated from a transformed mouse 3T3 cell line;Cahilly-Snyder;Somat Cell Mol Genet,1987
2. Structure of the MDM2 oncoprotein bound to the p53 tumor suppressor transactivation domain;Kussie;Science,1996
3. The mdm-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivation;Momand;Cell,1992
4. Mdm2 promotes the rapid degradation of p53;Haupt;Nature,1997
5. Oncoprotein MDM2 is a ubiquitin ligase E3 for tumor suppressor p53;Honda;FEBS Lett,1997
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