Polysubstituted 4,6-bis(hetero)arylpyrimidines as dual inhibitors of nitric oxide and prostaglandin E 2 production
Author:
Funder
Czech Academy of Sciences
Technology Agency of the Czech Republic
Publisher
Elsevier BV
Subject
Cancer Research,Clinical Biochemistry,Physiology,Biochemistry
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1. Molecular properties prediction, anticancer and anti-inflammatory activities of some pyrimido[1,2-b]pyridazin-2-one derivatives;BioImpacts;2023-10-10
2. Polysubstituted Pyrimidines as Potent Inhibitors of Prostaglandin E 2 Production: Increasing Aqueous Solubility;ChemMedChem;2021-06-19
3. Development of Scalable Synthesis of 5-Butyl-4-(4-methoxyphenyl)-6-phenylpyrimidin-2-amine (WQE-134), a Dual Inhibitor of Nitric Oxide and Prostaglandin E2 Production;Organic Process Research & Development;2020-08-28
4. Polysubstituted Pyrimidines as mPGES‐1 Inhibitors: Discovery of Potent Inhibitors of PGE 2 Production with Strong Anti‐inflammatory Effects in Carrageenan‐Induced Rat Paw Edema;ChemMedChem;2020-06-04
5. Influence of the C-5 substitution in polysubstituted pyrimidines on inhibition of prostaglandin E2 production;European Journal of Medicinal Chemistry;2018-08
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