Carbohydrates engineered at antibody constant domains can be used for site-specific conjugation of drugs and chelates
Author:
Publisher
Elsevier BV
Subject
Immunology,Immunology and Allergy
Reference42 articles.
1. Initial clinical results with technetium-99m-labeled LL2 monoclonal antibody fragment in the radioimmunodetection of B-cell lymphomas;Baum;Cancer,1994
2. Humanization of an anti-p185HER2 antibody for human cancer therapy;Carter;Proc. Natl. Acad. Sci. U.S.A.,1992
3. X-ray structures of the antigen-binding domains from three variants of humanized anti-p185HER2 antibody 4D5 and comparison with molecular modeling;Eigenbrot;J. Mol. Biol.,1993
4. Glycosylation of the variable region of immunoglobulin G-site specific maturation of the sugar chains;Endo;Mol. Immunol.,1995
5. Clinical utility of radioimmunoscintigraphy of non-Hodgkin's lymphoma with radiolabeled LL2 monoclonal antibody, LymphoSCAN: preliminary results;Gasparini;Tumori,1995
Cited by 16 articles. 订阅此论文施引文献 订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献
1. A glyco-engineering approach for site-specific conjugation to Fab glycans;mAbs;2022-11-29
2. Recent Chemical Approaches for Site‐Specific Conjugation of Native Antibodies: Technologies toward Next‐Generation Antibody–Drug Conjugates;ChemBioChem;2019-07-17
3. New linker structures applied in glycosite-specific antibody drug conjugates;Organic Chemistry Frontiers;2019
4. Straightforward Glycoengineering Approach to Site-Specific Antibody–Pyrrolobenzodiazepine Conjugates;ACS Medicinal Chemistry Letters;2016-09-22
5. Chemoenzymatic Conjugation of Toxic Payloads to the Globally Conserved N-Glycan of Native mAbs Provides Homogeneous and Highly Efficacious Antibody–Drug Conjugates;Bioconjugate Chemistry;2015-06-10
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线，采集、加工和组织学术论文而形成的新型学术文献查询和分析系统，可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容，当前同舟云学术共收录了国内外主流学术期刊6万余种，收集的期刊论文及会议论文总量共计约1.5亿篇，并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询！咨询电话：010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3