A glyco-engineering approach for site-specific conjugation to Fab glycans-Reference-Cited by-同舟云学术

A glyco-engineering approach for site-specific conjugation to Fab glycans

Published:2022-11-29 Issue:1 Volume:15 Page:
ISSN:1942-0862
Container-title:mAbs
language:en
Short-container-title:mAbs

Author:

Jaramillo Maria L.¹,Sulea Traian¹,Durocher Yves¹,Acchione Mauro¹,Schur Melissa J.²,Robotham Anna²,Kelly John F.²,Goneau Marie-France²,Robert Alma¹,Cepero-Donates Yuneivy¹,Gilbert Michel²^ORCID

Affiliation:

1. Human Health Therapeutics Research Centre, National Research Council Canada, 6100 Royalmount Avenue, H4P 2R2, Montreal, Qc, Canada

2. Human Health Therapeutics Research Centre, National Research Council Canada, 100 Sussex Drive, K1A 0R6, Ottawa, ON, Canada

Funder

This work was supported by the National Research Council Canada

Publisher

Informa UK Limited

Subject

Immunology,Immunology and Allergy

Link

https://www.tandfonline.com/doi/pdf/10.1080/19420862.2022.2149057

Reference42 articles.

1. Antibody−Drug Conjugates: Linking Cytotoxic Payloads to Monoclonal Antibodies

2. Site-specific antibody drug conjugates for cancer therapy

3. Site-specific conjugation of a cytotoxic drug to an antibody improves the therapeutic index

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5. Mutually Orthogonal Nonsense-Suppression Systems and Conjugation Chemistries for Precise Protein Labeling at up to Three Distinct Sites

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