New linker structures applied in glycosite-specific antibody drug conjugates-Reference-Cited by-同舟云学术

New linker structures applied in glycosite-specific antibody drug conjugates

Published:2019 Issue:17 Volume:6 Page:3144-3149
ISSN:2052-4129
Container-title:Organic Chemistry Frontiers
language:en
Short-container-title:Org. Chem. Front.

Author:

Faridoon Faridoon¹²³⁴⁵,Shi Wei¹²³⁴⁵,Qin Ken¹²³⁴⁵,Tang Yubo¹²³⁴⁵,Li Mingjie¹²³⁴⁵,Guan Dongliang¹²³⁴⁵,Tian Xiaobo¹²³⁴⁵,Jiang Bofeng¹²³⁴⁵,Dong Jinhua⁶⁷⁸⁹¹⁰,Tang Feng¹²³⁴⁵,Huang Wei¹²³⁴⁵^ORCID

Affiliation:

1. CAS Key Laboratory of Receptor Research

2. CAS Center for Excellence in Molecular Cell Science

3. Center for Biotherapeutics Discovery Research

4. Shanghai Institute of Materia Medica

5. Chinese Academy of Sciences

6. Key Laboratory of Structure-Based Drug Design and Discovery

7. Ministry of Education

8. Shenyang Pharmaceutical University

9. Shenyang

10. China

Abstract

Two new linkers employed in glycosite-specific antibody–drug conjugates demonstrate efficient conjugation, enhanced stability, and fluorescence properties.

Funder

National Natural Science Foundation of China

National Key New Drug Creation and Manufacturing Program, Ministry of Science and Technology

China Postdoctoral Science Foundation

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2019/QO/C9QO00646J

Reference35 articles.

1. Antibody-drug conjugates