Design, synthesis and antiproliferative activity of novel substituted 2-amino-7,8-dihydropteridin-6(5H)-one derivatives-Reference-Cited by-同舟云学术

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Design, synthesis and antiproliferative activity of novel substituted 2-amino-7,8-dihydropteridin-6(5H)-one derivatives

Published:2017-09 Issue:17 Volume:27 Page:3954-3958
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Li Qiu,Yang Hai-Kui,Sun Qi,You Wen-Wei,Zhao Pei-Liang

Funder

National Natural Science Foundation of China

Outstanding Young Teachers in Guangdong Province

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference29 articles.

1. Bondy SS, McFadden R, PCT WO 2017035230.

2. Discovery and Structural Optimization of N5-Substituted 6,7-Dioxo-6,7-dihydropteridines as Potent and Selective Epidermal Growth Factor Receptor (EGFR) Inhibitors against L858R/T790M Resistance Mutation

3. Pyrimido[4,5-d]pyrimidin-4(1H)-one Derivatives as Selective Inhibitors of EGFR Threonine790to Methionine790(T790M) Mutants

4. Development of a Practical Synthesis of a TORC1/2 Inhibitor: A Scalable Application of Memory of Chirality

5. Dihydropteridinone Inhibitors of BRD4

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1. Bicyclic 6-6 Systems: Pteridines;Comprehensive Heterocyclic Chemistry IV;2022

2. Development of pteridin-7(8H)-one analogues as highly potent cyclin-dependent kinase 4/6 inhibitors: Synthesis, structure-activity relationship, and biological activity;Bioorganic Chemistry;2021-11

3. Design, synthesis and antiproliferative activity of novel 2,4-diamino-5-methyleneaminopyrimidine derivatives as potential anticancer agents;Bioorganic & Medicinal Chemistry Letters;2021-09

4. Polymer-Supported Synthesis of Various Pteridinones and Pyrimidodiazepinones;Molecules;2021-03-14

5. Novel [1,2,4]triazolo[1,5-a]pyrimidine derivatives as potent antitubulin agents: Design, multicomponent synthesis and antiproliferative activities;Bioorganic Chemistry;2019-11

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