Pyrimido[4,5-d]pyrimidin-4(1H)-one Derivatives as Selective Inhibitors of EGFR Threonine790to Methionine790(T790M) Mutants-Reference-Cited by-同舟云学术

Pyrimido[4,5-d]pyrimidin-4(1H)-one Derivatives as Selective Inhibitors of EGFR Threonine790to Methionine790(T790M) Mutants

Published:2013-06-26 Issue:32 Volume:52 Page:8387-8390
ISSN:1433-7851
Container-title:Angewandte Chemie International Edition
language:en
Short-container-title:Angew. Chem. Int. Ed.

Author:

Xu Tianfeng,Zhang Lianwen,Xu Shilin,Yang Chao-Yie,Luo Jinfeng,Ding Fang,Lu Xiaoyun,Liu Yingxue,Tu Zhengchao,Li Shiliang,Pei Duanqing,Cai Qian,Li Honglin,Ren Xiaomei,Wang Shaomeng,Ding Ke

Publisher

Wiley

Subject

General Chemistry,Catalysis

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1002/anie.201302313/fullpdf

Reference17 articles.

1. Gefitinib or Carboplatin–Paclitaxel in Pulmonary Adenocarcinoma

2. Screening for Epidermal Growth Factor Receptor Mutations in Lung Cancer

3. Structures of Lung Cancer-Derived EGFR Mutants and Inhibitor Complexes: Mechanism of Activation and Insights into Differential Inhibitor Sensitivity

4. Kinetic Analysis of Epidermal Growth Factor Receptor Somatic Mutant Proteins Shows Increased Sensitivity to the Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor, Erlotinib

5. The T790M mutation in EGFR kinase causes drug resistance by increasing the affinity for ATP

Cited by 30 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Theoretical study of the effect of the solvent on the electronic properties of pyrimidopyrimidine derivatives;Computational and Theoretical Chemistry;2023-09

2. Discovery of Isoform-Selective Akt3 Degraders Overcoming Osimertinib-Induced Resistance in Non-Small Cell Lung Cancer Cells;Journal of Medicinal Chemistry;2022-09-29

3. Discovery of Hexahydrofuro[3,2-b]furans as New Kinase-Selective and Orally Bioavailable JAK3 Inhibitors for the Treatment of Leukemia Harboring a JAK3 Activating Mutant;Journal of Medicinal Chemistry;2022-07-21

4. 1,3‐Diazepine: A privileged scaffold in medicinal chemistry;Medicinal Research Reviews;2021-03

5. The increasing impact of Chinese innovative drug research on the global stage with a focus on drug discovery;Expert Opinion on Drug Discovery;2020-06-17