Design, synthesis, and antiviral properties of 4′-substituted ribonucleosides as inhibitors of hepatitis C virus replication: The discovery of R1479-Reference-Cited by-同舟云学术

Design, synthesis, and antiviral properties of 4′-substituted ribonucleosides as inhibitors of hepatitis C virus replication: The discovery of R1479

Published:2007-05 Issue:9 Volume:17 Page:2570-2576
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Smith David B.,Martin Joseph A.,Klumpp Klaus,Baker Stewart J.,Blomgren Peter A.,Devos Rene,Granycome Caroline,Hang Julie,Hobbs Christopher J.,Jiang Wen-Rong,Laxton Carl,Pogam Sophie Le,Leveque Vincent,Ma Han,Maile Graham,Merrett John H.,Pichota Arkadius,Sarma Keshab,Smith Mark,Swallow Steven,Symons Julian,Vesey David,Najera Isabel,Cammack Nick

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference22 articles.

1. Epidemiology of Hepatitis C: Geographic Differences and Temporal Trends

2. Inhibition of the Subgenomic Hepatitis C Virus Replicon in Huh-7 Cells by 2′-Deoxy-2′-Fluorocytidine

3. Synthesis and anti-viral activity of a series of d- and l-2′-deoxy-2′-fluororibonucleosides in the subgenomic HCV replicon system

4. Design, Synthesis, and Antiviral Activity of 2‘-Deoxy-2‘-fluoro-2‘-C-methylcytidine, a Potent Inhibitor of Hepatitis C Virus Replication

5. Inhibition of Hepatitis C Virus RNA Replication by 2′-Modified Nucleoside Analogs

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