An enantioselective and modular platform for C4ʹ-modified nucleoside analogue synthesis enabled by intramolecular trans-acetalizations-Reference-Cited by-同舟云学术

An enantioselective and modular platform for C4ʹ-modified nucleoside analogue synthesis enabled by intramolecular trans-acetalizations

Published:2024-08-17 Issue:1 Volume:15 Page:
ISSN:2041-1723
Container-title:Nature Communications
language:en
Short-container-title:Nat Commun

Author:

Nuligonda Thirupathi,Kumar Gautam,Wang Jason W.,Rajapaksha Dinithi,Elayan Ismael A.^ORCID,Demir Ramiz^ORCID,Meanwell Neil J.,Wang Sherrie F.,Mahal Lara K.^ORCID,Brown Alex^ORCID,Meanwell Michael W.^ORCID

Funder

-Striving for Pandemic Preparedness - The Alberta Research Consortium -NSERC Discovery Grant

Canada Excellence Research Chairs, Government of Canada

North Island College Professional Development Fund

NSERC PGS-D

the Digital Research Alliance of Canada

Publisher

Springer Science and Business Media LLC

Link

https://www.nature.com/articles/s41467-024-51520-5.pdf

Reference39 articles.

1. Shelton, J. et al. Metabolism, biochemical actions, and chemical synthesis of anticancer nucleosides, nucleotides, and base analogs. Chem. Rev. 116, 14379–14455 (2016).

2. Seley-Radtke, K. L. & Yates, M. K. The evolution of nucleoside analogue antivirals: a review for chemists and non-chemists. Part I: early structural modifications to the nucleoside scaffold. Antivir. Res. 154, 66–86 (2018).

3. Yates, M. K. & Seley-Radtke, K. L. The evolution of nucleoside analogue antivirals: a review for chemists and non-chemists. Part II: complex modifications to the nucleoside scaffold. Antivir. Res. 162, 5–21 (2019).

4. Galmarini, C. M., Mackey, J. R. & Dumontet, C. Nucleoside analogues and nucleobases in cancer treatment. Lancet Oncol. 3, 415–424 (2002).

5. Bege, M. & Borbás, A. The medicinal chemistry of artificial nucleic acids and therapeutic oligonucleotides. Pharmaceuticals 15, 909–948 (2022).